Core Scientific Thesis

The Cross-Kingdom Hypothesis

Polysaccharides from marine organisms, fungal cell walls, and plant mucilages share structural and immunological properties that interact synergistically with cannabinoids, terpenes, and alkaloids. No competitor has modeled this interaction space computationally.

Our platform is built to model, predict, and validate these cross-kingdom interactions using a Message Passing Neural Network (MPNN) with 98.11% GenomePath prediction accuracy β€” generating 21,000+ novel molecular combinations with formation probability, synergy scores, and condition-specific therapeutic potential.

This is a predictive systems biology approach, not a chemical lookup table.

Explore NeuroBotanica

Key Research Metrics

Clinical Studies Analyzed505+
Dimeric Predictions21,000+
GenomePath Accuracy98.11%
Analytical Path Modules31 (trade secrets)
Cannabis Compounds Modeled184 unique cannabinoids
Kingdoms4 (cannabis, marine, fungal, plant)
Patent Status2 filed + 1 in progress
The Four Kingdoms

Where the Science Lives

Each kingdom contributes a distinct compound class. Cross-kingdom synergy is where the therapeutic innovation happens.

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Cannabis

320+ Studies

THC, CBD, CBN, CBG, CBDV and 12 additional cannabinoids + 4 active metabolites. 16 neuropsychiatric conditions, pain, epilepsy, oncology support.

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Marine Polysaccharides

75+ Studies

Fucoidan, carrageenan, ulvan from seaweed. Immunomodulation, oncology support, anti-inflammatory. TLR2/4 receptor modeling.

πŸ„

Fungal Therapeutics

60+ Studies

Beta-glucans, hericenones, cordycepin, lentinan. Neuroprotection, immune enhancement, cognitive support. Dectin-1 receptor modeling.

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Plant Polysaccharides

50+ Studies

Galactomannans, rhamnogalacturonans, pectins. Glycemic control, gut health, topical therapeutics. Ayurvedic and European TK validation.

Methods

How the Platform Works

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MPNN Prediction Engine

Message Passing Neural Network models molecular interactions across compound classes. 98.11% accuracy on GenomePath TK→Genomic validation. Predicts synergy before synthesis.

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Dimeric Prediction Framework

Generates 21,000+ novel molecular combinations with formation probability, synergy scores, and condition-specific therapeutic potential across all four kingdoms.

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Traditional Knowledge Integration

EthnoPath module integrates validated traditional knowledge into compound discovery pathways. FPIC-governed, consent-logged, and attribution-tracked via VeriTrad.

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Demographic Bias Correction

EquiPath integration detects and corrects demographic bias in all predictions. 96% accuracy. Ensures recommendations work across populations β€” not just overrepresented groups.

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Regulatory Pathway Analysis

RegPath module maps each compound to FDA and DSHEA pathways. GRAS notifications, NDI submissions, clinical trial design β€” regulatory readiness built into the platform.

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Evidence Tier Architecture

Every recommendation is ranked by evidence quality β€” meta-analysis, RCT, cohort, in vitro, traditional use. Transparent, reproducible, auditable at every step.

Intellectual Property

Patent Portfolio

Cannabis Therapeutics Provisionalβœ… Filed Dec 22, 2025
Polysaccharide Therapeutics Provisional⏰ March 2026
EquiPath Bias Detection ProvisionalπŸ“‹ Q2 2026
VeriTrad PCT (International)πŸ“‹ September 2026

Partner With Our Research

Dispensaries, researchers, academic institutions, and community organizations. There is a structured partnership pathway for each.